Targeting early-onset Parkinson’s with AI

What is AlphaFold and how does it work? AlphaFold is a computational modeling tool developed by the Wellcome Sanger Institute (WSI) and University College London (UCL) to predict the 3D structure of proteins based on their amino acid sequence. This can be used to understand how proteins fold, which helps in determining their function and potential therapeutic targets. The tool has been applied to a wide range of diseases and conditions, including Parkinson’s disease and Alzheimer’s, as well as in the diagnosis of genetic disorders like hemophilia and Huntington’s disease. The algorithm is designed to be accessible for researchers with varying levels of expertise, making it a valuable tool for both basic and applied bioinformatics.